Change of MicroRNA-134, CREB and p-CREB expression in epileptic rat
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چکیده
منابع مشابه
Beta-boswellic acid and ethanolic extract of Olibanum regulate the expression levels of CREB-1 and CREB-2 genes
Physiological studies confirm improvement of memory by Olibanum, a resin from Boswellia species, while little is known about the molecular mechanism by which it affects memory performance. Two master transcription factors, CREB-1 and CREB-2, regulate downstream memory-related genes expression, leading to the long-term memory potentiation. This study addresses the effects of Beta-boswellic acid ...
متن کاملBeta-boswellic acid and ethanolic extract of Olibanum regulate the expression levels of CREB-1 and CREB-2 genes
Physiological studies confirm improvement of memory by Olibanum, a resin from Boswellia species, while little is known about the molecular mechanism by which it affects memory performance. Two master transcription factors, CREB-1 and CREB-2, regulate downstream memory-related genes expression, leading to the long-term memory potentiation. This study addresses the effects of Beta-boswellic acid ...
متن کاملEffect of 8 weeks aerobic training on SRT1, CREB and BDNF genes expression in hippocampus of Wistar rats
Abstract Introduction & Objective: Exercise through BDNF induces its beneficial effects on the brain. However, its cellular mechanisms are not fully understood. Thus, the purpose of this study was to investigate the effect of 8 weeks aerobic training on mRNA expression of SIRT1, CREB and BDNF genes in hippocampus of male Wistar rats. Methods:Twelve 8-week-old rats were the subjects of this stud...
متن کاملVRK1 phosphorylates CREB and mediates CCND1 expression.
Vaccinia virus B1 kinase plays a key role in viral DNA replication. The homologous mammalian vaccinia-related kinases (VRKs) are also implicated in the regulation of DNA replication, although direct evidence remains elusive. Here we show that VRK1 regulates cell cycle progression in the DNA replication period by inducing cyclin D1 (CCND1) expression. Furthermore, depletion of VRK1 in human canc...
متن کاملEarly odor preference learning in the rat: bidirectional effects of cAMP response element-binding protein (CREB) and mutant CREB support a causal role for phosphorylated CREB.
Early odor preference learning in rats is associated with increases of phosphorylated CREB (pCREB) in mitral cells of the olfactory bulb. In the present study, herpes simplex virus expressing CREB (HSV-CREB) and dominant-negative mutant CREB (HSV-mCREB) have been injected into the bulb to assess a causal role for CREB and pCREB in this model. Odor paired with stroking or with the beta-adrenocep...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Medicine
سال: 2015
ISSN: 1995-7645
DOI: 10.1016/s1995-7645(14)60333-3